The Lancet began as an independent, international weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue (October 5, 1823), the journal has emphasised two distinct objectives—to inform and to reform. In Wakley's words: "A lancet can be an arched window to let in the light or it can be a sharp surgical instrument to cut out the dross and I intend to use it in both senses." In more modern times, these twin goals are expressed in four domains of our work: medical research, clinical practice, global health, and news and comment. The journal's editors will collaborate over any contribution that advances or illuminates medical science or practice, or that educates or engages readers on important matters in the practice, policy, and politics of research, medicine, and public health.
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