Dr. Hugh-Jones trained in neuroscience at Imperial College, London. He went on to qualify as a physician at Charing Cross and Westminster Medical School. He completed internal medicine boards while practicing at Chelsea and Westminster Hospital, and St. Mary's Hospital, London, becoming a Member of the Royal College of Physicians. He then entered the radiology fellowship program at the Royal Postgraduate Medical School, Hammersmith Hospital, London. He joined Schering AG/Bayer AG in 2001 where he worked in the Oncology Strategic Business Unit based in New Jersey providing global medical leadership to several key brands. He subsequently moved to Enzon Pharmaceuticals initially as Vice President of Medical Affairs and then as Vice President of Global Business Management. Dr. Hugh-Jones joined Sanofi-Aventis as head of U.S. Medical Affairs Oncology. With the integration of Genzyme he headed up Medical Affairs, North America for Sanofi Oncology, Hematology and Solid Organ Transplantation. At the end of 2012 was named Chief Medical Officer, Sanofi U.S.