The transparent tissues of the eye allow light to reach the retina. This highly metabolic tissue requires oxygen delivered by the blood vessels, which are damaged by disease. Diabetic retinopathy is the commonest cause of blindness in the working-age population and in later life hypertension adds to this toll. The eyes maybe the mirror of the soul, but they certainly are a window into our general health. This lecture traces the story from the development of the ophthalmoscope to modern treatments.
As well as being the Gresham Professor of Physic, Professor William Ayliffe is a Consultant Ophthalmologist in the NHS and at the Lister Hospital in London. In addition to being a practicing clinician and teacher, he also continues to carry out clinical research into the prevention of blindness.
After taking a first in Immunology at Imperial College, Professor Ayliffe qualified in Medicine in St. Bartholomew's Hospital London. Specializing in inflammatory eye diseases and corneal and cataract surgery he held a research registrar post at Oxford, before training in clinical ophthalmology in Bristol, Manchester and Harvard USA. His PhD was on mechanisms of corneal transplant failure. He has worked in developing countries and also with ORBIS, the international flying eye hospital. In addition to general ophthalmology, Professor Ayliffe has developed a local and tertiary referral service for cornea, uveitis and inflammatory eye disease.
Professor Ayliffe is a winner of the prestigious Wix Prize for the History of Medicine and the Kabi-Pharmacia Prize for immunological mechanisms of corneal transplant rejection. He is a Reviewer for a number of professional journals including Eye, British Journal of Ophthalmology, Journal of Cataract and Refractive Surgery, he is an Examiner for the Royal College of Ophthalmologists and an Advisor to the UK Transplant Service. He has undertaken wide media and TV work for the national press, the BBC and Channel 4, has an extensive range of publications and has delivered prestigious lectures all over the world.