The Sage Commons is a novel information platform being built by an international partnership of researchers and stakeholders to define the molecular basis of disease and guide the development of effective human therapeutics and diagnostics.
The Sage Commons will be used to integrate diverse molecular mega-data sets, to build predictive bionetworks and to offer advanced tools proven to provide unique new insights into human disease biology. Users will also be contributors that advance the knowledge base and tools through their cumulative participation.
The public access mission of the Sage Commons requires the development of a new strategic and legal framework to protect the rights of contributors while providing widespread access to integrative genomics resources.
Andrea Califano is the Principal Investigator at Califano Lab. Dr. Califano's interests are broadly defined within the field of Systems Biology, with specific application to human malignancies. In particular his lab has spearheaded early efforts to assemble genome-wide, context-specific maps of molecular interactions in human cells, by integrating several reverse engineering approaches. These maps have shown significant promise in the rational elucidation of both physiological and pathological phenotypes.